How Much Bromelain to Take for Inflammation?

Bromelain dosage for inflammation

TL; DR Summary:

Bromelain dosage for inflammation is between 200-400mg with a glass of water. You can also take it with food, although this would potentially diminish bromelain’s effects on your digestion. Bromelain however is not potent enough to reduce inflammation substantially on its own. If your main issue is joint pain, you will want to check our guide to the current 3 best-reviewed joint supplements.

Let’s Talk About Bromelain

Bromelain is an enzyme found in the pineapple plant. It is most effective as an anti-inflammatory which can be used to treat osteoarthritis, gout, and other inflammation-related conditions. [1] The enzyme is well absorbed when taken orally and is best taken on an empty stomach. [2]

Some experts categorize bromelain as a beneficial enzyme that helps with acute and chronic inflammation of the mouth, a common problem for people with diabetes. It is also recommended for treating wounds, burns, and ulcers. Bromelain is typically available in supplement form, so it is best to take it at the same time each day. It can also be added to foods and drinks such as juices, soups, and smoothies for maximum absorption. Bromelain starts working fairly fast, within 30-60 minutes of ingestion, depending on whether you take it with food as well as your metabolic speed.

Acute and chronic inflammation are very common with diseases such as osteoarthritis. [3] Bromelain is also effective at treating wounds, burns, and ulcers, specifically those associated with a lack of blood flow like diabetic ulcers. It is also effective for reducing inflammation in the stomach, which is why it is sometimes used to treat heartburn. Bromelain is also found in some toothpaste to help fight gum disease.

Taking bromelain can also help with digestion, specifically reducing inflammation and the irritation of irritable bowel syndrome. It is also effective at helping to treat constipation, intestinal gas, and diarrhea. Side effects of Bromelain are uncommon but may include swelling or redness in the mouth and throat, stomach cramping or pain, diarrhea, and throat irritation.

How can Bromelain Help with Inflammation?

Bromelain helps to relieve inflammation and pain by reducing the activity of molecules responsible for the inflammatory response called proteases. In addition, it may help prevent scarring by limiting the activity of molecules responsible for collagen breakdown.

Bromelain also contains protease inhibitors, which may limit pain and inflammation by preventing the breakdown of natural molecules in the body.

Supplemental sources of bromelain include pineapple, papaya, mango, and apple. Bromelain may help relieve pain and swelling in the body after exercise, particularly from joint injuries or muscle tears. It may also decrease recovery time and the time needed for injured joints to heal. What’s more, bromelain can lower your inflammation by decreasing the number of inflammatory proteins that are produced in your body.

Bromelain is also a good choice for a supplement because it possesses secondary anti-inflammatory and antioxidant properties. Meaning, it may be able to boost your native antioxidants. This chemical is also a natural blood thinner and may lower the risk of stroke by decreasing plaque build-up in arteries.

Bromelain Dosage for Inflammation

Bromelain dosage for Inflammation can range from 100mg to 400mg per day, but the exact dosage will depend on the person’s health condition and how severe the inflammation is. Nevertheless, this dose is fairly low when compared to the bromelain dosage for digestion and stomach support. As such, you should find it easy to stick to daily supplementation of bromelain, whether as a standalone supplement, or just as one of many supplements in your stack.



  1. Bottega R, Persico I, De Seta F, Romano F, Di Lorenzo G. Anti-inflammatory properties of a proprietary bromelain extract (Bromeyal™) after in vitro simulated gastrointestinal digestion. Int J Immunopathol Pharmacol. 2021 Jan-Dec;35:20587384211034686. doi: 10.1177/20587384211034686. PMID: 34387509; PMCID: PMC8366142.
  2. Pavan R, Jain S, Shraddha, Kumar A. Properties and therapeutic application of bromelain: a review. Biotechnol Res Int. 2012;2012:976203. doi: 10.1155/2012/976203. Epub 2012 Dec 10. PMID: 23304525; PMCID: PMC3529416.
  3. Sokolove J, Lepus CM. Role of inflammation in the pathogenesis of osteoarthritis: latest findings and interpretations. Ther Adv Musculoskelet Dis. 2013 Apr;5(2):77-94. doi: 10.1177/1759720X12467868. PMID: 23641259; PMCID: PMC3638313.

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