Physiosleep Review: Does it Work?

Physiosleep review

Physiosleep Summarized

Physiosleep is a sleep aid featuring melatonin and Zylaria extract as key ingredients. It employs dual-release technology for sustained sleep support, but lacks common sleep aid ingredients like magnesium and valerian root. It should improve your sleep to an extent, but with just 2 ingredients, it’s not the bes value for the $39.95 that it costs. Are there better alternatives out there? Sure, but they also require forking out a little bit more than this one!


  1. Contains melatonin, a well-studied sleep regulator.
  2. Includes Zylaria extract, a potential sleep enhancer (underresearched, though)
  3. Utilizes dual-release technology for extended effects.


  1. Lacks commonly used sleep aid ingredients such as magnesium, valerian root, passionflower, and l-theanine.
  2. May not suit individuals sensitive to or allergic to fungus (due to Zylaria extract).

What do we recommend?

-Click to See The Current 3 Best-Reviewed Sleep Aids-

About Physiosleep

PhysioSleep is a marketed as a “next-generation” sleep aid that contains two main clinically-tested ingredients designed to support the body’s natural sleep cycle. It is marketed as a solution for those who want to fall asleep faster, stay asleep longer, and wake up feeling refreshed​​.

At this point it’s hard to come by a supplement that has claims that we haven’t already heard. The only question we’re interested in is – does it really work?

What’s Inside?

The two key ingredients in PhysioSleep are pharmaceutical-grade melatonin (1 mg) and Zylaria extract (500mg). These ingredients are delivered to the bloodstream at precise times via a special dual-release technology, which aids in supporting the sleep cycle throughout the night.

The melatonin helps regulate the sleep-wake cycle, and is generally considered safe for short-term use. [1, 2] Zylaria, or Xylaria Nigripes, is a type of fungus that has been studied for its potential calming and sleep-enhancing properties. [3] The lack of human evidence for the latter, though, means there are better sleep aids that could’ve been put in its stead – such as magnesium, l-theanine, and hops.

The dose of melatonin at 1mg is within the typical range found in many sleep aids, while the 500mg of Zylaria extract is a substantial dosage that reflects the manufacturer’s confidence in its effectiveness.

In addition to the active ingredients, Physiosleep also contains Microcrystalline cellulose, dicalcium phosphate, hydroxypropyl methylcellulose (HPMC), stearic acid, croscarmellose sodium, silica, and magnesium stearate. These compounds are primarily used as fillers, binders, and anti-caking agents in the manufacturing process.

Are the Ingredients in Physiosleep Good?

The ingredients used in PhysioSleep have individually undergone multiple clinical trials, including double-blind placebo-controlled trials, to establish their efficacy and safety. Melatonin is a hormone naturally produced by the body and is known to regulate sleep-wake cycles. On the other hand, Zylaria is a proprietary extract, and while the exact nature of it is not specified on the PhysioSleep website, it is described as a premium ingredient designed to support sleep​​.

Dosage Instructions (How to Take)

For optimal results, take one capsule of PhysioSleep with a glass of water 30 to 60 minutes before going to sleep daily. Each bottle contains 30 capsules, providing a 30-day sleep aid dosage​​.

What do Others Say?

At the time of writing, I couldn’t find specific customer reviews for PhysioSleep. I recommend checking online marketplaces and health forums for real user experiences and reviews.

Have you already tried Physiosleep? Let us know how it worked for you.

Side Effects of Physiosleep?

While PhysioSleep is designed to be safe and extremely effective for nearly every healthy person, it’s not suitable for pregnant or lactating mothers, or children under the age of 18. Those with allergies, particularly to soy, should also consult their physician before taking the supplement. If you have a medical condition or take prescription medications, it’s advised to show a bottle of PhysioSleep to your physician for proper approval​​.

Cost & Value

PhysioSleep is offered in a few different packages. The Starter Pack, containing one bottle (30-day supply), costs $39.95 plus $5.95 for shipping within the U.S. The Most Popular Pack includes three bottles (90-day supply) at a discounted rate of $33.31 per bottle with free shipping. The Best Value Pack offers six bottles (180-day supply) at $29.99 per bottle with free shipping. Additionally, PhysioSleep comes with a 180-day money-back guarantee. If you’re not happy with the results, you can get your money back.

Physiosleep Review: The Bottom Line

PhysioSleep is a sleep aid supplement designed to help people struggling with sleep disorders. Its formula, consisting of melatonin and Zylaria extract, aims to help users fall asleep faster and have a more restful sleep. Th money-back guarantee provides a risk-free opportunity to try the product. However, the price that is being charged for PhysioSleep makes us hesitant to recommend it over other alternatives that have much more comprehensive formulas.

What do we recommend?

-Click to See The Current 3 Best-Reviewed Sleep Aids-


  1. Costello RB, Lentino CV, Boyd CC, O’Connell ML, Crawford CC, Sprengel ML, Deuster PA. The effectiveness of melatonin for promoting healthy sleep: a rapid evidence assessment of the literature. Nutr J. 2014 Nov 7;13:106. doi: 10.1186/1475-2891-13-106. PMID: 25380732; PMCID: PMC4273450.
  2. Savage RA, Zafar N, Yohannan S, et al. Melatonin. [Updated 2022 Aug 8]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from:
  3. Zhao Z, Li Y, Chen H, Huang L, Zhao F, Yu Q, Xiang Z, Zhao Z. Xylaria nigripes mitigates spatial memory impairment induced by rapid eye movement sleep deprivation. Int J Clin Exp Med. 2014 Feb 15;7(2):356-62. PMID: 24600489; PMCID: PMC3931588.,receptors%20of%20GABA%20%5B20%5D.

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