The Food and Drug Administration (FDA) is issuing this proposed rule and seeking public comment to put into effect a final monograph for nonprescription, over-the-counter (OTC) sunscreen drug products. This proposed rule describes the conditions under which FDA proposes that OTC sunscreen monograph products are generally recognized as safe and effective (GRASE) and not misbranded. It is being published as part of the ongoing review of OTC drug products conducted by FDA.
Cancer is a leading cause of mortality worldwide. While the defining feature of cancer is uncontrolled division of abnormal cells, it is a complex disease with varied presentations (i.e., different etiologies and target tissues) that involves dysregulation of multiple interconnected signaling pathways. Diverse environmental factors have been associated with the development and progression of various cancer types. A critical question in the field of environmental health is how to harness what is known about cancer biology and associated environmental exposures to improve public health outcomes.
The Converging on Cancer Workshop is aimed at providing a clear path forward for evaluating the interactions between environmental exposures and cancer biology using the latest tools in toxicology and identifying knowledge gaps that require research attention. Potential applications of this understanding include building a framework for incorporating mechanistic data into cancer risk assessment, developing effective screening tools to detect the carcinogenic potential of environmental chemicals (including mixtures), engineering safer products, and designing more effective multi-target therapeutics.
This free meeting is open to the public with attendance limited only by the space available. The meeting will consist of plenary sessions which will be webcast, breakout discussion sessions, and a poster session. The plenary sessions will be webcast but the breakout sessions and poster session will not be webcast.
The European Food Safety Authority (EFSA) will hold a workshop where applicants can share their experiences with implementing the Guidance on Human and Animal Health Aspects of the Risk Assessment of the Application of Nanoscience and Nanotechnologies in the Food and Feed Chain.
The document takes account of scientific developments related to human and animal health since publication of the previous guidance in 2011, particularly regarding physico-chemical characterisation, exposure assessment and hazard characterisation of nanomaterials.
The guidance also details nano-specific considerations when performing in vivo/in vitro studies and outlines a tiered framework for toxicological assessment.
The guidance is applicable to novel foods, food contact materials (FCMs), food/feed additives and pesticides. Its correct implementation is important for applicants that seek market approval/renewal of a product under the various food laws, as well as for regulatory risk assessors from EFSA, Member States, and stakeholders. Since the new novel food legislation came into force in January 2018, it has been mandatory for the most up-to-date test methods to be used in risk assessments.
Members of the public may attend in person. More information is available at this EFSA website.
The National Academies of Sciences, Engineering, and Medicine (NASEM), New Voices in Sciences, Engineering, and Medicine, will hold a meeting titled "STEM Workforce Diversity: Where Do We Go from Here?" New Voices, a cohort of emerging leaders in science, engineering, and medicine, is pleased to host these distinguished panelists representing government and industry for an in-depth discussion on efforts to diversify the national science, engineering, and health workforce.
Featured panelists include:
- Paul Dabbar: Under Secretary for Science, Department of Energy
- Sylvia James: Acting Deputy Assistant Director, National Science Foundation
- Rich Lockwood: Vice President, Lockheed Martin Corporation
- Dave Parrillo: Global R&D Director, The Dow Chemical Company
- Hannah Valantine: Chief Officer for Scientific Workforce Diversity, National Institutes of Health
- Sonia Zarate: Program Officer, Howard Hughes Medical Institute
Members of the public may attend in person or via webcast. Registration information for in-person or webcast attendance is available at this website, and additional information is available at this NASEM website.
AZCentral – The Food and Drug Administration wants to take a closer look at the ingredients and labeling for sunscreens, hoping to update regulations that the commissioner said have not been changed “in literally decades.”
Nano.gov – To celebrate the 15-year anniversary of the National Nanotechnology Initiative (NNI), the National Nanotechnology Coordination Office is rolling out a number of activities to showcase the discoveries enabled by this collaborative effort and the significant impacts these discoveries are having on society.
Berkeley News – Inserting or tweaking genes in plants is more art than science, but a new technique developed by University of California, Berkeley, scientists could make genetically engineering any type of plant—in particular, gene editing with CRISPR-Cas9—simple and quick.
NPR – The commissioner of the Food and Drug Administration, Scott Gottlieb, announced Tuesday that he is resigning the position, effective in one month.
Stat News – The National Institutes of Health on Thursday apologized for its past failures to recognize and address the culture of sexual harassment that has impacted scientists for generations.
MIT Technology Review – We asked Gates to choose this year’s list of inventions that will change the world for the better.